Key topics of interest for treatment strategies identified in the Delphi exercise grouped according to the PICO format
| Patients | Intervention & Comparators | Outcome |
|---|---|---|
| Diagnosis | Cyclophosphamide | Disease-related outcomes |
| Granulomatosis with Polyangiitis | Rituximab | Treatment-related adverse events |
| Microscopic Polyangiitis | Mycophenolate | |
| Eosinophilic Granulomatosis with Polyangiitis | Methotrexate | |
| Disease severity | Azathioprine | |
| New-onset disease | Glucocorticoids | |
| Relapsing disease | Avacopan | |
| Organ- or life-threatening disease | Mepolizumab | |
| Not organ- or life-threatening disease | Plasma exchange |