Question | AS Probands Sensitivity no/total (%) | HLA-B27 negative Relatives Specificity no/total (%) | OR (95% CI) | P value | ||
Lumbar Spine region Chronic inflammatory low backpain (Calin) | 64/87 | 73.6 | 117/138 | 84.8 | 15.50 (7.97 to 30.16) | <0.00001 |
Insidious onset of back pain | 72/86 | 83.7 | 80/138 | 58.0 | 7.09 (3.65 to 13.79) | <0.00001 |
More than 3 months duration | 67/86 | 77.9 | 103/138 | 74.6 | 10.38 (5.48 to 19.63) | <0.00001 |
Associated with morning stiffness >30 min | 66/86 | 76.7 | 102/138 | 73.9 | 9.35 (4.99 to 17.52) | <0.00001 |
Back pain starting before age 40 | 84/86 | 97.7 | 88/138 | 63.8 | 73.92 (17.43 to 33.45) | <0.00001 |
Pain and stiffness | 68/87 | 78.2 | 105/138 | 76.1 | 11.39 (5.99 to 21.63) | <0.00001 |
Worsening at early morning | 56/86 | 65.1 | 125/137 | 91.2 | 19.44 (9.28 to 40.75) | <0.00001 |
Waking up during the night because of complaints | 56/86 | 65.1 | 122/138 | 88.4 | 14.23 (7.18 to 28.22) | <0.00001 |
Leaving bed and walking around during the night | 50/84 | 59.5 | 131/136 | 96.3 | 38.53 (14.26 to 104.08) | <0.00001 |
Pain irradiating into gluteal region | 64/82 | 78.0 | 91/138 | 65.9 | 6.88 (3.66 to 12.93) | <0.00001 |
Usage of analgesics | 82/86 | 95.3 | 86/138 | 62.3 | 33.90 (11.73 to 97.96) | <0.00001 |
Relief of symptoms due to analgesics | 73/88 | 83.0 | 88/137 | 64.2 | 8.74 (4.53 to 16.85) | <0.00001 |
Thoracic region | ||||||
Complaints at thoracic region ever | 67/84 | 79.8 | 106/134 | 79.1 | 14.92 (7.59 to 29.33) | <0.00001 |
Pain and stiffness | 47/88 | 53.4 | 131/138 | 94.9 | 21.45 (9.01 to 51.11) | <0.00001 |
Complaints at early morning | 54/86 | 62.8 | 116/138 | 84.1 | 8.90 (4.73 to 16.73) | <0.00001 |
Morning stiffness at thoracic spine region | 45/84 | 53.6 | 132/137 | 96.4 | 30.46 (11.31 to 82.03) | <0.00001 |
Complaints if body position does not change | 52/83 | 62.7 | 119/137 | 86.9 | 11.09 (5.70 to 21.58) | <0.00001 |
Usage of analgesics | 48/85 | 56.5 | 129/137 | 94.2 | 20.92 (9.09 to 48.12) | <0.00001 |
Relief of symptoms due to analgesics | 46/87 | 52.9 | 130/138 | 94.2 | 18.23 (7.96 to 41.76) | <0.00001 |
Ventral chest wall region | ||||||
Complaints at ventral chest wall region ever | 62/86 | 72.1 | 113/136 | 83.1 | 12.69 (6.62 to 24.32) | <0.00001 |
Included items are presented by anatomical region and have sensitivity and/or specificity >70%.
AS, ankylosing spondylitis.