Table 1

Clinical characteristics of participants with rheumatic and musculoskeletal diseases who withheld perivaccination mycophenolate

ParticipantAgeSexRaceDiagnosisVaccine typeMycophenolate doseNumber of doses heldConcurrent therapyAntibody titre *Flare
136MWhiteCT-ILD†Moderna2000 mg3No>250No
262FWhiteCT-ILD†Pfizer500 mg88Prednisone>250No
319FWhiteIA‡Pfizer1000 mg5Abatacept16Yes
458FWhiteIA‡Pfizer2000 mg28Tofacitinib>250No
546FWhiteMyositisJ+J2000 mgNAPrednisone82No
653FWhiteMyositisJ+J2500 mg56Prednisone206No
746FWhiteMyositisPfizer3000 mg20IVIG§, HCQ¶40No
854FWhiteMyositisPfizer3000 mgNANo<0.40No
935FWhiteMyositisModerna3000 mg24No>250No
1071FWhiteOverlap CTD**Moderna2000 mg4Rituximab9.0No
1158FWhiteOverlap CTD**Moderna2000 mg9HCQ¶, Prednisone8No
1255FWhiteOverlap CTD**Moderna2000 mg30HCQ¶, Prednisone8No
1364FWhiteOverlap CTD**Pfizer500 mg38No>250No
1470MWhiteSclerodermaModerna3000 mg42Rituximab<0.40Yes
1536FWhiteSclerodermaPfizer3000 mg14No35No
1640FWhiteSclerodermaPfizer2500 mg28No244No
1742FWhiteSclerodermaPfizer3000 mg8Abatacept22No
1863FWhiteSjogren’sPfizer2500 mgNANo12No
1949FWhiteSLE††J+J3000 mg13No>250No
2054FWhiteSLE††Moderna1000 mg10HCQ‡>250No
2150FBlackSLE††Pfizer3000 mg98Belimumab, Prednisone>250No
2231FWhiteSLE††Pfizer2000 mg10HCQ‡, Prednisone80No
2338FWhiteSLE††Pfizer1500 mg20Prednisone168No
2451FWhiteSLE††Moderna1000 mg5Abatacept>250No
  • *The assay ranges from<0.4 to >250 units/mL. Positive antibody was defined as an anti-SARS-CoV-2 receptor binding domain antibody titre>0.79 units/mL.

  • †Denotes connective tissue disease-related ILD.

  • ‡Rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, reactive arthritis, or inflammatory bowel disease-associated arthritis.

  • §Intravenous immunoglobulin.

  • ¶Hydroxychloroquine.

  • **Denotes a combination of two or more of the rheumatic conditions.

  • ††Systemic lupus erythematosus.