Table 4

Flares and AEs stratified by inflammatory RMD disease group

Inflammatory joint diseases (n=2977)Connective tissue diseases (n=928)Vasculitis (n=593)
Flare following vaccinationYes151 (5)29 (3)19 (3)
No2260 (76)784 (85)561 (95)
Unknown/missing566 (19)115 (12)13 (2)
Severity of flareMild/minor51 (2)13 (1)5 (1)
Moderate77 (3)12 (1)8 (1)
Severe/major without hospitalisation15 (1)1 (<1)3 (1)
Severe/major with hospitalisation1 (<1)2 (<1)3 (1)
Unknown/missing7 (<1)1 (<1)
New medication or dosage increase due to flare44 (1)10 (1)11 (2)
Vaccine-related AEsYes1092 (37)382 (41)175 (30)
No1885 (63)546 (59)418 (70)
AE severity (only collected for AEs of special interest)Non-serious55 (2)21 (2)13 (2)
Severe – important medical event4 (1)4 (1)
Severe – hospitalisation (or prolongation of existing hospitalisation)4 (1)2 (<1)
Severe – life threatening2 (<1)1 (<1)
Unknown/missing2 (<1)
  • All values are n (%) unless stated otherwise.

  • AEs, adverse events; RMD, rheumatic and musculoskeletal disease.