Table 2

Investigations and laboratory results on diagnosis among children and adults with NJI in Iceland, 2003–2017

Children <2 years2–18 yearsTotalAdults 18–65 years>65 yearsTotalP value
No of cases192140149110259
Admission data:
 Temperature (median, °C)38383837.737.637.7 0.02
 WCC (median, x109/L)13.210.911.49.911.610.50.4
 ESR (median, mm/hour)343535547157 0.006
 CRP (median, mg/L)494849123180148 <0.001
 Synovial fluid WCC (median, x106)*86 67531 07531 07550 40069 00058 7940.3
 Positive blood culture†3/16 (19)7/15 (47)10/31 (32)32/100 (32)42/79 (53)74/179 (41)0.4
 Crystal arthropathy¶5/60 (8)22/63 (35)27/123 (22)
Normal admission values:‡
 Temperature <37.8°C6/19 (32)8/21 (38)14/40 (35)78/141 (55)59/102 (58)137/246 (56) 0.02
 WCC <10.5×109/L6/19 (32)10/21 (48)16/40 (40)84/143 (59)41/109 (38)125/252 (50)0.3
 CRP <10 mg/L2/19 (10.5)4/21 (19)6/40 (15)4/143 (3)6/107 (6)10/250 (4) 0.01
 ESR <20 mm/hour1/10 (10)1/7 (14)2/17 (12)11/70 (16)7/49 (14)18/119 (15)1
Other infective syndromes:
 Adjacent osteomyelitis3/19 (16)9/21 (43)12/40 (30)16/149 (11)13/110 (12)29/259 (11) 0.005
 Endocarditis0003/149 (2)4/110 (4)7/259 (3)
 Cellulitis0003/149 (2)3/110 (3)6/259 (2)
 Other§0003/149 (2)5/110 (5)8/259 (3)
  • Data are no/no (%).

  • P value, children vs adults.

  • P values <0.05 are shown in bold.

  • *Information on number of WCC in the synovial fluid obtained was found in 171 adult cases and 12 paediatric cases.

  • †Information on blood culture (whether taken, positive or negative) was found in: all paediatric cases, 141 cases in age group 18–65 years and 103 cases >65 years. Blood culture was performed in 16/19 <2 years, 15/21 cases 2–18 years, 100/149 cases 18–65 years and 79/110 >65 years.

  • ‡Information on (A) temperature was found in: all paediatric cases, 144/149 cases 18–65 years and 102/110 >65 years. (B) WCC: all paediatric cases, 143/149 cases 18–65 years and 109/110 >65 years. (C) CRP: all paediatric cases, 143/149 cases 18–65 years, 107/110 >65 years. (D) ESR: 10/19 cases <2 years, 7/21 cases 2–18 years, 70/149 cases 18–65 years and 49/110 >65 years.

  • §Pneumonia 5 (all patients were >65 years), urinary tract infection 2, streptococcal toxic shock syndrome one patient.

  • ¶Information on concurrent crystal arthropathy in adults was found in: 60/149 cases 18–65 and 63/110 >65 years.

  • CRP, C reactive protein; ESR, erythrocyte sedimentation rate; NJI, native joint infection; WCC, white cell count.