ANA sensitivity and specificity per ANA titre as per metaregression of published data on 13 080 patients with SLE4 2017, American College of Rheumatology
Cut-off | Sensitivity | Specificity | ||
ANA titre | % | 95% CI | % | 95% CI |
1:40 | 98.4 | 97.6 to 99.0 | 66.9 | 57.8 to 74.9 |
1:80 | 97.8 | 96.8 to 98.5 | 74.7 | 66.7 to 81.3 |
1:160 | 95.8 | 94.1 to 97.1 | 86.2 | 80.4 to 90.5 |
1:320 | 86.0 | 77.0 to 91.9 | 96.6 | 93.9 to 98.1 |
ANA, antinuclear antibodies; SLE, systemic lupus erythematosus.