Rates of treatment response and treatment failure
| PBO/PDN (n=94) | TCZ/PDN (n=130) | P value* | |
| Treatment response, n (%) | 27 (28.7) | 86 (66.2) | |
| Treatment failure, n (%) | 67 (71.3) | 44 (33.8) | <0.0001 |
| Refractory disease | 31 (33.0) | 18 (13.8) | |
| Disease relapse | 36 (38.3) | 26 (20.0) |
*Cochran-Mantel-Haenszel test comparing the proportions of patients with treatment failure between the PBO/PDN group and the TCZ/PDN group adjusted for baseline prednisone dose (≤30 mg/day or >30 mg/day).
PBO/PDN, placebo+prednisone; TCZ/PDN, tocilizumab+prednisone.