Table 2

Incidence rates of cardiovascular events in veterans with rheumatoid arthritis (per 1000 person-years)

Event category*NFollow-up time (PY)Mean time to event, yearsIncidence rates (per 1000 PY)IRR (95% CI)
MTX ever-exposedMTX never-exposed
Composite37810 3603.4233.0539.880.83 (0.67 to 1.02)
HF hospitalisation8710 9563.475.1710.66 0.48 (0.30 to 0.77)
MACE34210 4433.4530.3235.140.86 (0.69 to 1.07)
CAD15110 6053.0813.5014.970.90 (0.65 to 1.26)
Stroke6610 9343.366.135.951.03 (0.62 to 1.72)
CVD Death16711 0983.9913.0017.030.76 (0.55 to 1.05)
  • Values listed in bold indicate p<0.05.

  • *MACE is a composite of outcomes included in CAD, stroke and CVD death. CAD includes acute myocardial infarction, percutaneous coronary intervention or coronary artery bypass.

  • .CAD, coronary artery disease; CVD, cardiovascular disease; HF, heart failure; IRR, incidence rate ratio; MACE, major adverse cardiovascular event; MTX, methotrexate; PY, person years; RA, rheumatoid arthritis.