Table 2

Empirical and estimated marginal means by study groups and treatment

GroupEmpirical mean (SD)EMM* (95% CI)
Controls9.36 (1.85)8.48 (8.12 to 8.85)
IMIDs all6.47 (3.14)6.90 (6.45 to 7.35)
IMIDs b/tsDMARDs6.49 (2.91)6.90 (6.22 to 7.58)
csDMARDs6.26 (3.00)6.67 (5.84 to 7.50)
Untreated6.64 (3.70)7.13 (6.30 to 7.96)
  • *Adjusted for age, sex, time elapsed from first vaccination date to sampling date.

  • bDMARDs, biological disease-modifying antirheumatic drugs; csDMARDs, conventional synthetic disease-modifying antirheumatic drugs; EMM, estimated marginal mean; IMIDs, immune-mediated inflammatory diseases; tsDMARDs, targeted-synthetic disease-modifying antirheumatic drugs.