Table 2

Eular recommendations in which IAT are mentioned

Joint/conditionEULAR recommendation
Knee osteoarthritis86‘Intra-articular injection of long acting GC is indicated for acute exacerbation of knee pain, especially if accompanied by effusion.’
‘Hyaluronic acid (…) is probably effective in knee OA, but the size effect is relatively small, suitable patients are not well defined, and pharmacoeconomic aspects of that treatment are not well established’.
Gout16‘Recommended first-line options for acute flares are colchicine (…), oral corticosteroid (…) or articular aspiration and injection of corticosteroids.’
Rheumatoid arthritis87 88‘Monitoring should be frequent (…) therapy should be adjusted.’
*Adjustment of therapy includes the optimisation of MTX (or other csDMARD) dose or route of administration, or intra-articular injections of GC in the presence of one or few residual active joints.
Hand osteoarthritis89 90‘Intra-articular injections of glucocorticoids should not generally be used in patients with hand OA, but may be considered in patients with painful interphalangeal joints’.
Acute or recent onset swelling of the knee91‘Intra-articular steroids should not be administered unless an appropriate diagnosis has been made and contraindications have been ruled out’.
  • csDMARD, conventional synthetic disease-modifying antirheumatic drugs ; GC, glucocorticoids; MTX, methotrexate; OA, osteoarthritis.