Association Between ASAS PR and ASDAS Clinical Thresholds (ID/LDA/HDA or VHDA)
| ASDAS ID (<1.3) | ASDAS LDA (1.3 to <2.1) | ASDAS HDA or VHDA (≥2.1) | |
| Continuous UPA Group | n=15 | n=31 | n=39 |
| ASAS PR Responders (n=16) | 11 | 5 | 0 |
| ASAS PR Non-responders (n=69) | 4 | 26 | 39 |
| PBO to UPA Group | n=25 | n=35 | n=25 |
| ASAS PR Responders (n=28) | 16 | 8 | 4 |
| ASAS PR Non-responders (n=57) | 9 | 27 | 21 |
P<0.001 for association of ASAS PR with the ordered ASDAS categories of ID-LDA-HDA, for both Continuous UPA Group and PBO to UPA Group. P-value calculated from Cochran-Armitage trend test for association of ordinal categories.
ASAS, Assessment of SpondyloArthritis international Society response criteria; ASDAS, AS Disease Activity Score; HDA, high disease activity; ID, inactive disease; LDA, low disease activity; PBO, placebo; PR, partial remission; UPA, upadacitinib; VHDA, very high disease activity.