Table 1.

The association between the change of the mSASSS over two years and current and/or previous treatment with TNFi in the longitudinal generalized estimation equation analysis.

TNFi treatment definition
Referenceβ*
(95% CI)
TNFi for ≥12 months in the previous 2-year intervalTNFi for ≥12 months in the current 2-year interval
YesNo TNFi for ≥12 months in the current 2-year interval-0.19
(-0.56 to 0.18)
YesNo TNFi for ≥12 months in the previous 2-year interval-0.56
(-0.95 to -0.17)
YesYesNo TNFi for ≥12 months in the current and previous 2-year intervals-0.59
(-1.03 to -0.15)
  • *Parameter estimates from the multivariable models adjusted for sex, symptom duration at the beginning of the current 2-year interval, time-averaged ASDAS in the current 2-year interval, smoking in the current 2-year interval, classification as non-radiographic or radiographic axSpA, and mSASSS at the beginning of the current 2-year interval.