Demographic data, clinical characteristics and treatment of the patients with confirmed and clinical COVID-19
Patient 1 | Patient 2 | Patient 3 | |
Diagnosis | Behçet’s disease | Rheumatoid arthritis | Ankylosin spondylitis |
Age, years | 40 | 60 | 65 |
Sex | F | M | F |
Comorbidities | – | Hypertension | Hypertension Hashimoto’s disease |
Disease status at last visit | Remission | Remission | Remission |
Diagnosis of the disease in years | 8 | 12 | 4 |
Use of corticosteroids | No | No | No |
Biological therapy: anti-TNF | Infliximab | Infliximab | Golimumab |
Date of the last infusion of anti-TNF | 03/16/2020 | 03/24/2020 | 03/31/2020 |
Symptom onset date—COVID-19 | 03/17/2020 | 04/31/2020 | 04/17/2020 |
Time interval between infusion and symptom onset in days | 1 | 38 | 17 |
RT-PCR COVID-19 (data) | 03/24/2020 | 05/11/2020 | 04/22/2020 |
Therapy instituted during treatment | Symptomatic medications | Azithromycin | Symptomatic medications |
Symptoms (duration of symptoms in days) | |||
Fever | No | Yes (1) | No |
Maximum temperature | 37.2 | 38.5 | 36.5 |
Non-productive cough | No | Yes (4) | Yes (10) |
Sputum production | No | No | No |
Rhinorrhea | Yes (1) | No | No |
Nasal congestion | Yes (1) | Yes (2) | Yes (8) |
Sore throat | No | No | Yes (2) |
Anorexia | Yes (2) | No | No |
Fatigue | Yes (4) | No | Yes (12) |
Myalgia | No | Yes (2) | Yes (5) |
Arthralgia | No | No | No |
Anosmia | Yes (9) | No | Yes (7) |
Dysgeusia | Yes (4) | No | Yes (8) |
Headache | Yes (2) | Yes (2) | Yes (2) |
Diarrhoea | No | No | Yes (2) |
Nausea | Yes (3) | No | No |
Vomiting | No | No | No |
Chest X-ray or CT scan | Not done | Not done | Not done |