Table 2

SNP showing genome-wide significant or suggestive associations with juvenile idiopathic arthritis in the meta-analysis

SNPChr.Position (bp)Notable genesRisk/non-risk alleleUK GWAS P valueUSA GWAS P valueMETA P valueMETA ORMETA 95% CIQ statisticQ P valueI2
rs26142586135 677 202 AHI1 A/G9.17E-086.50E-069.47E-121.171.12–1.220.180.670
rs79815064346 277 577 CCR3 A/G7.61E-088.43E-053.31E-111.251.17–1.340.870.350
rs124303031343 032 027 TNFSF11 C/T3.61E-069.23E-041.88E-091.141.09–1.190.560.450
rs7647909371 200 157 FOXP1 G/T4.56E-065.27E-052.02E-091.171.11–1.2300.960
rs70435059117 628 528 TNFSF8 A/G3.74E-060.0083338.27E-081.121.07–1.171.090.30.08
rs116928672100 759 477 AFF3 G/A4.57E-060.0041529.26E-081.131.08–1.190.590.440
rs72657048125 289 734 RUNX3 G/C3.90E-060.0081383.51E-071.131.08–1.180.690.410
  • bp, base pair; Chr., chromosome; GWAS, genome-wide association study; SNP, single nucleotide polymorphism.