Table 1

Clinical characteristics of patients with lupus nephritis carrying TLR1 minor allele (rs142003616)

PatientGenderAge at diagnosisEuropean descentACR 1ACR 2ACR 3ACR 4ACR 5ACR 6ACR 7ACR 8ACR 9ACR 10ACR 11AutoAbs*Biopsy everWHO-class†
3 F16YesYesNoYesYesYesYesYesYesNoNoYesN:N:NYesUnknown
5F15YesYesNoNoNoYesNoYesNoYesYesYesY:N:NYesIV d
6 F39YesNoNoNoNoNoNoYesNoYesYesYesY:N:YYesV b
  • ACR classification criteria,7 8 ACR 1: malar rash, ACR 2: discoid rash, ACR 3: photosensitivity, ACR 4: oral ulcer, ACR 5: non-erosive arthritis, ACR 6: pleuritis or pericarditis, ACR 7: renal disorder, ACR 8: neurological disorder, ACR 9: haematological disorder, ACR 10: immunologic disorder, ACR 11: positive ANA.

  • *Autoantibodies, anti-ds-DNA: anti-Sm: anti-phospholipid antibodies, respectively.

  • †WHO-classification of lupus nephritis.

  • ‡The case represented in the text. The detailed clinical characteristics of all patients with SLE (855 with SLE, of whom 292 had LN) can be found in Bolin K et al.9

  • AutoAbs, autoantibodies; LN, lupus nephritis; N, no; SLE, systemic lupus erythematosus; Y, yes.