Clinical characteristics of patients with lupus nephritis carrying TLR1 minor allele (rs142003616)
| Patient | Gender | Age at diagnosis | European descent | ACR 1 | ACR 2 | ACR 3 | ACR 4 | ACR 5 | ACR 6 | ACR 7 | ACR 8 | ACR 9 | ACR 10 | ACR 11 | AutoAbs* | Biopsy ever | WHO-class† |
| 1 | F | 16 | Yes | Yes | No | No | No | Yes | No | Yes | No | No | Yes | Yes | Y:N:N | No | – |
| 2 | F | 26 | Yes | Yes | No | Yes | No | Yes | No | Yes | No | Yes | Yes | Yes | Y:Y:N | No | – |
| 3 | F | 16 | Yes | Yes | No | Yes | Yes | Yes | Yes | Yes | Yes | No | No | Yes | N:N:N | Yes | Unknown |
| 4 | F | 53 | Yes | Yes | Yes | Yes | No | Yes | No | Yes | Yes | No | No | Yes | N:N:Y | Yes | V |
| 5 | F | 15 | Yes | Yes | No | No | No | Yes | No | Yes | No | Yes | Yes | Yes | Y:N:N | Yes | IV d |
| 6‡ | F | 39 | Yes | No | No | No | No | No | No | Yes | No | Yes | Yes | Yes | Y:N:Y | Yes | V b |
ACR classification criteria,7 8 ACR 1: malar rash, ACR 2: discoid rash, ACR 3: photosensitivity, ACR 4: oral ulcer, ACR 5: non-erosive arthritis, ACR 6: pleuritis or pericarditis, ACR 7: renal disorder, ACR 8: neurological disorder, ACR 9: haematological disorder, ACR 10: immunologic disorder, ACR 11: positive ANA.
*Autoantibodies, anti-ds-DNA: anti-Sm: anti-phospholipid antibodies, respectively.
†WHO-classification of lupus nephritis.
‡The case represented in the text. The detailed clinical characteristics of all patients with SLE (855 with SLE, of whom 292 had LN) can be found in Bolin K et al.9
AutoAbs, autoantibodies; LN, lupus nephritis; N, no; SLE, systemic lupus erythematosus; Y, yes.