Table 4

Trajectory of multimorbidity in patients with incident rheumatoid arthritis (RA) compared with patients without RA

A. Primary analysis
(n=44 conditions)
B. Secondary analysis*
(n=36 conditions)
C. 2 years preindex date
(n=44 conditions)
β (95% CI)P valueβ (95% CI)P valueβ (95% CI)P value
RA vs non-RA1.13 (1.10 to 1.17)<0.0010.62 (0.59 to 0.64)<0.0010.29 (0.27 to 0.31)<0.001
Year of follow-up0.24 (0.23 to 0.24)<0.0010.18 (0.18 to 0.19)<0.0010.48 (0.47 to 0.49)<0.001
RA × time (years)0.21 (0.20 to 0.21)<0.0010.12 (0.11 to 0.13)<0.0010.33 (0.32 to 0.35)<0.001
Age (per year)0.06 (0.06 to 0.06)<0.0010.05 (0.05 to 0.05)<0.0010.04 (0.04 to 0.04)<0.001
Female sex0.28 (0.24 to 0.32)<0.0010.15 (0.12 to 0.18)<0.0010.16 (0.12 to 0.20)<0.001
  • A and B. n=61 528 patients and 173 469 observations.

  • C. N=33 202 patients and 153 121 observations.

  • *Excluded conditions known to be related to RA or could be misclassified as RA.

  • RA, rheumatoid arthritis.