Age | Gender | Race | COVID-19 Dx method | COVID-19 symptoms | Admission | Tx for COVID-19 | Clinical manifestations of SLE/other autoimmune disease | Serologies | SLE medications | Other comorbidities | |
1 | 49 | F | C | RT-PCR | Cough | No | HCQ, Zinc | LN, pleuritis, anaemia, lymphopenia, SS | ANA, anti-dsDNA, anti-Smith, anti-RNP, ACA, hypocomplementemia | Azathioprine, prednisone (5 mg/day) | Obese (BMI 40) |
2 | 48 | F | H | Rapid antigen | SOB, diarrhoea | Yes | Oxygen, convalescent plasma, azithromycin | LN, neuropsychiatric lupus, APLS | ANA, anti-dsDNA, anti-SSA, ACA, hypocomplementemia | Prednisone (10 mg/day), coumadin, rituximab infusion on 2/2020 | Overweight (BMI 26) |
3 | 40 | F | H | RT-PCR | Cough, fever, SOB, chest pain | Yes | Oxygen | Arthritis, malar rash, pleuritis, alopecia, APLS | ANA, anti-dsDNA, anti-RNP, anti-Smith, anti-SSA, LA, ACA, anti-B2GP1, hypocomplementemia | Prednisone (6 mg/day), azathioprine, HCQ, coumadin | Obese (BMI 32) |
4 | 49 | F | AA | RT-PCR | Fever, chills, cough | No | Supportive care | Arthritis, alopecia, LN, anaemia, leucopenia, thrombocytopenia | ANA, anti-dsDNA, anti-RNP, anti-Smith, anti-SSA, anti-SSB, ACA, hypocomplementemia | Prednisone (7.5 mg/day), rivaroxaban (not APLS), MMF, HCQ | Obese (BMI 42) |
5 | 56 | F | C | Rapid antigen | Headache | No | Supportive care | Malar rash, photosensitivity, alopecia, LN, thrombocytopenia | ANA, anti-SSA, hypocomplementemia | Prednisone (5 mg/day), azathioprine, HCQ | None |
6 | 49 | F | H | RT-PCR | Fever, chills, headaches, vomiting, diarrhoea, loss of smell, sore throat, cough | No | Supportive care | Arthritis, alopecia, photosensitivity, ITP | ANA, anti-dsDNA, LA | HCQ | Obese (BMI 30) |
7 | 48 | F | H | Antibody | Fever, cough, fatigue, myalgias, nasal congestion | No | Supportive care | Malar rash, photosensitivity, alopecia, Raynaud’s, arthritis, neuropsychiatric lupus | ANA, anti-dsDNA, anti-smith, anti-RNP, anti-SSA, anti-chromatin, hypocomplementemia | MMF, HCQ | Dyslipidaemia, HTN, DVT, PE, obese (BMI 35), ILD |
8 | 48 | F | H | RT-PCR | Cough, SOB, URI symptoms | Yes | Oxygen, steroids, convalescent plasma | Arthritis, Raynaud’s, photosensitivity, alopecia, oral ulcers, malar rash, SS | ANA, anti-dsDNA, anti-SSA, anti-B2GP1, hypocomplementemia | Prednisone (5 mg/day), HCQ | Overweight (BMI 28) |
9 | 48 | F | H | N/A | Fever, cough, fatigue, | No | Supportive care | Arthritis, lymphopenia, LN | ANA, anti-dsDNA, anti-RNP, anti-Smith, anti-SSA, anti-SSB, LA, ACA, anti-B2GP1, hypocomplementemia | Prednisone (20 mg/day), HCQ, MMF, belimumab | None |
10 | 26 | F | H | RT-PCR | Loss of taste and smell | No | Supportive care | Malar rash, alopecia, arthritis, photosensitivity | ANA, anti-dsDNA, anti-RNP, anti-Smith, anti-SSA, LA, ACA, hypocomplementemia | Prednisone (5 mg/day), HCQ | None |
Shaded subjects had anti-interferon α autoantibodies.
AA, African-America; ACA, anti-cardiolipin antibody; ANA, anti-nuclear antibody; anti-B2GP1, anti-beta2 glycoprotein; anti-dsDNA, anti-double stranded DNA; anti-RNP, anti-ribonucleoprotein; anti-SSA, anti–Sjögren’s-syndrome-related antigen A; anti-SSB, anti–Sjögren’s-syndrome-related antigen B; APLS, anti-phospholipid syndrome; BMI, Body mass index; C, Caucasian; DVT, deep vein thrombosis; F, female; H, Hispanic; HCQ, hydroxychloroquine; HTN, hypertension; ILD, interstitial lung disease; ITP, Idiopathic thrombocytopenic purpura; LA, lupus anticoagulant; LN, lupus nephritis; MMF, mycophenolate mofetil; N/A, not available; PE, pulmonary embolism; SLE, systemic lupus erythematosus; SOB, shortness of breath; SS, Sjögren’s syndrome; URI, upper respiratory infection.