Baseline characteristics of patients with RA treated without and with early intensive treatment
| No early intensive treatment | Early intensive treatment | |
| (n=353) | (n=945) | |
| Inclusion period | 1993–2000 | 2001–2016 |
| Women, n (%) | 238 (67) | 620 (66) |
| Age in years, mean (SD) | 56 (16) | 58 (15) |
| Symptom duration, days median (IQR) | 136 (75–279) | 117 (58–234) |
| Current smoker, n (%) | 98 (30) | 211 (25) |
| ESR, median (IQR) | 37 (21–58) | 29 (14–45) |
| 66-SJC, median (IQR) | 10 (5–16) | 6 (3–11) |
| RF-positive, n (%) | 193 (55) | 543 (59) |
| ACPA-positive, n (%) | 199 (56) | 456 (51) |
ACPA, anti-citrullinated peptide antibody; ESR, erythrocyte sedimentation rate; RF, rheumatoid factor; SJC, swollen joint count.