Effect of treatment (vs control) on outcomes, univariable and multivariable analyses
| Effect of treatment versus control Univariable analysis HR or coefficient (95% CI) | Effect of treatment versus control Multivariable analysis* HR or coefficient (95% CI) | |
| Primary outcome | ||
| Clinical improvement (2 points) in WHO score† | 1.79 (1.20 to 2.67) | 2.31 (1.45 to 3.68) |
| Key secondary outcomes | ||
| Hospital mortality† | 0.35 (0.19 to 0.65) | 0.26 (0.13 to 0.52) |
| Mechanical ventilation† | 0.29 (0.14 to 0.60) | 0.22 (0.10 to 0.52) |
| Other key secondary outcomes | ||
| Clinical improvement (1 point) in WHO score† | 1.95 (1.33 to 2.87) | 2.26 (1.44 to 3.54) |
| Independence from oxygen therapy† | 1.80 (1.19 to 2.71) | 2.36 (1.45 to 3.83) |
| Duration of mechanical ventilation in survivors‡ | −2.57 (−12.08 to 6.93) | −6.83 (−21.45 to 7.79) |
| Duration of hospitalisation in survivors‡ | −5.23 (−8.99 to −1.46) | −6.65 (−10.93 to −2.37) |
*Adjusted for age, gender, body mass index, smoking status, hypertension, diabetes, cardiovascular disease and arrhythmia.
†Results from Cox regression models.
‡Results from linear regression models.
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