Table 1

Definitions of remission according to clinical, serological and therapeutic status allowed

Disease activityTreatment
SLEDAI-2KPGAPDNAntimalarials, biologics, immunosuppressants*
ClinicalSerological
PDN ≤5 mg/dayRegardlessRegardlessRegardless≤5 mg/dayRegardless
PGA <0.5RegardlessRegardless<0.5RegardlessRegardless
cSLEDAI=00RegardlessRegardlessRegardlessRegardless
PDN ≤5 mg/day plus PGA <0.5RegardlessRegardless<0.5≤5 mg/dayRegardless
cSLEDAI=0 plus PGA <0.50Regardless<0.5RegardlessRegardless
cSLEDAI=0 plus PDN ≤5 mg/day0RegardlessRegardless≤5 mg/dayRegardless
cSLEDAI=0 plus PDN ≤5 mg/day plus PGA <0.50Regardless<0.5≤5 mg/dayRegardless
  • *Stable well-tolerated doses.

  • cSLEDAI, clinical systemic lupus erythematosus Disease Activity Index 2000; PDN, prednisone equivalent; PGA, physician global assessment.