Impact of baseline smoking status on treatment outcomes
| Comparison | Odds Ratio (95% CI) | p | |
|---|---|---|---|
| DAS28-remission 1 yr, yes vs. no* | Never vs. current smoker | 1.43 (1.27;1.62) | <0.001 |
| Previous vs. current | 1.14 (0.99;1.30) | 0.07 | |
| CDAI remission 1 yr, yes vs. no* | Never vs. current | 1.53 (1.34;1.75) | <0.001 |
| Previous vs. current | 1.29 (1.11;1.50) | <0.001 | |
| Comparison | Hazard Ratio (95% CI) | p | |
| Start of bDMARD during follow-up** | Never vs current smoker | 0.85 (0.76;0.96) | 0.006 |
| Previous vs. current | 1.05 (0.93;1.19) | 0.4 |
*Logistic regression analyses (adjusted for gender and age)
** Cox regression analyses (adjusted for gender and age)