Demographic and clinical data of patients with and without calcinosis.
| Demographic and clinical data | Calcinosis (n=10) | No calcinosis (n=15) | p-value |
|---|---|---|---|
| Female gender, n (%) | 9 (90) | 12 (80) | 0.626 |
| Age (years), median [min,max] | 68.5 [27, 75] | 52 [36, 73] | 0.129 |
| Cutaneous classification | |||
| Limited, n (%) | 9 (90) | 7 (46.7) | 0.04 |
| Diffuse, n (%) | 1 (10) | 3 (20) | 0.626 |
| Early, n (%) | 0 (0) | 2 (13.3) | 0.500 |
| Overlap, n (%) | 0 (0) | 3 (20) | 0.250 |
| Clinical manifestations | |||
| Current or previous digital ulcers, n (%) | 5 (50) | 6 (40) | 0.697 |
| Interstitial lung disease, n (%) | 2 (20) | 4 (26.7) | 1.000 |
| Pulmonary hypertension, n (%) | 2 (20) | 1 (6.7) | 0.550 |
| Arthritis, n (%) | 2 (20) | 3 (20) | 1.000 |
| Calcinosis, n (%) | 3 (30) | 0 (0) | 0.052 |
| Esophageal involvement, n (%) | 6 (60) | 6 (40) | 0.428 |
| NFC patterns | |||
| Non specific abnormalities, n (%) | 1 (10) | 3 (20) | 0.626 |
| Early scleroderma, n (%) | 1 (10) | 1 (6.7) | 1.000 |
| Active scleroderma, n (%) | 3 (30) | 10 (58.8) | 0.111 |
| Late scleroderma, n (%) | 4 (40) | 1 (6.7) | 0.121 |
| Autoantibodies | |||
| Centromere B, n (%) | 7 (70) | 8 (53.3) | 0.678 |
| Scl-70, n (%) | 1 (10) | 4 (26.7) | 0.615 |