Hazard ratios for VTE events
Parameter | csDMARDs | TNFi | Other bDMARDs |
---|---|---|---|
N | 3500 | 5060 | 2534 |
VTE event | 38 (1.1) | 55 (1.1) | 23 (0.9) |
Age [years] | 58.8 (12.6) | 56.5 (12.9) | 58.1 (12.4) |
Female sex | 2575 (73.6) | 3734 (73.8) | 1933 (76.3) |
Disease duration [years] | 6.2 (7.2) | 9.4 (8.6) | 11.9 (9.2) |
Seropositivity | 2189 (62.6) | 3739 (73.9) | 2048 (80.8) |
Joint erosions | 1024 (31.0) | 2566 (52.4) | 1523 (63.3) |
Prior bDMARD therapies | 0 (0.2) | 0.3 (0.6) | 1.2 (1.2) |
CRP | 8.8 (8.1) | 11.6 (10.6) | 12.4 (11.8) |
DAS28-ESR | 4.4 (1.3) | 4.9 (1.2) | 5.1 (1.3) |
% of full physical capacity | 71.3 (21.8) | 66.2 (22.6) | 62.1 (23.5) |
Current glucocorticoid therapy | 2564 (73.3) | 3951 (78.1) | 2036 (80.4) |
Heart failure | 36 (1) | 113 (2.2) | 93 (3.7) |
Coronary artery disease | 196 (5.6) | 326 (6.4) | 183 (7.2) |
Cerebrovascular disease | 60 (1.7) | 86 (1.7) | 44 (1.7) |
Osteoporosis | 400 (11.4) | 771 (15.2) | 530 (20.9) |
Ever smoker | 1875 (53.6) | 2738 (54.1) | 1402 (55.3) |
Results are presented as mean ± SD or number (percentage).