Table 2.

Hazard ratios for VTE events

ParametercsDMARDsTNFiOther bDMARDs
N350050602534
VTE event38 (1.1)55 (1.1)23 (0.9)
Age [years]58.8 (12.6)56.5 (12.9)58.1 (12.4)
Female sex2575 (73.6)3734 (73.8)1933 (76.3)
Disease duration [years]6.2 (7.2)9.4 (8.6)11.9 (9.2)
Seropositivity2189 (62.6)3739 (73.9)2048 (80.8)
Joint erosions1024 (31.0)2566 (52.4)1523 (63.3)
Prior bDMARD therapies0 (0.2)0.3 (0.6)1.2 (1.2)
CRP8.8 (8.1)11.6 (10.6)12.4 (11.8)
DAS28-ESR4.4 (1.3)4.9 (1.2)5.1 (1.3)
% of full physical capacity71.3 (21.8)66.2 (22.6)62.1 (23.5)
Current glucocorticoid therapy2564 (73.3)3951 (78.1)2036 (80.4)
Heart failure36 (1)113 (2.2)93 (3.7)
Coronary artery disease196 (5.6)326 (6.4)183 (7.2)
Cerebrovascular disease60 (1.7)86 (1.7)44 (1.7)
Osteoporosis400 (11.4)771 (15.2)530 (20.9)
Ever smoker1875 (53.6)2738 (54.1)1402 (55.3)
  • Results are presented as mean ± SD or number (percentage).