Characteristics of treatment of PsA and AxS patients
| PsA (n=1829) | AxS (n=908) | Difference (95% CI) | |
|---|---|---|---|
| Female (%, n) | 55.1% (1007) | 29.1% (264) | 26 (22.2 to 29.6)* |
| Mean age at diagnosis (years, SD) | 46.9 (14) | 43.5 (14.4) | 3.4 (2.3 to 4.5)* |
| BMI (Index, SD) | 30.3 (6.3) | 28 (5.8) | 2.3 (1.8 to 2.8)* |
| Time from symptom to diagnosis (years, SD) | 8.9 (5.5) | 8.0 (5.6) | 0.9 (0.5 to 1.3) |
| Hypertension at diagnosis (%, n) | 24.2% (442/1829) | 19.4% (176/908) | 4.8 (1.5 to 8.0)* |
| Time from diagnosis to biologic (years, SD) | 6.3 (4.7) | 6.1 (5.0) | 0.2 (-0.9 to 0.5) |
| Used a Biologic (%, n) | 23% (420/1829) | 36.8% (334/908) | 13.8 (10.2 to 17.5)* |
| NSAIDs used pre-biologic (SD) | 11.3 (3.2) | 11.6 (3.2) | 0.3 (-0.2 to 0.8) |
| Number of DMARDs used pre-biologic (SD) | 3.1 (1.5) | 2.5 (1.7) | 0.6 (0.4 to 0.8)* |
| Biologic treatment change/failure (%, n) | 21.6% (92/425) | 22% (74/336) | 0.4 (-6.4 to 5.5) |
| Sicknotes issued by GPᵻ pre-biologic (SD) | 33.9% (144/425) | 33.6% (113/336) | 0.3 (-6.5 to 7.0) |
| Sicknotes issued by GP ᵻ post-biologic (SD) (%, n) | 19.3% (82/425) | 16.7% (56/336) | 2.6 (-2.9 to 8.0) |
| Hospitalised for serious infection pre- diagnosis (%, n) | 7.2% (131/1829) | 6.3% (57/908) | 0.9 (-1.2 to 2.8) |
| Hospitalised for serious infection post- diagnosis (%, n) | 10.4% (190/1829) | 11.6% (105/908) | 1.2 (-1.3 to 3.8) |
| Hospitalised for serious infection post- biologic (%, n) | 5.6% (24/425) | 6.3% (21/336) | 0.7 (-2.8 to 4.2) |
* Significant at p<0.05
ᵻ General practioner/Primary care physician