Supplementary Table 8

Stepwise conditional analysis on HLA-DQα1:160D in combined cohort, using gender as covariate

CHRMarkerCaseControlNon-reference amino-acidOR (95% CI)P value
6DRB1:96:H0.530.64DRB1:96:H0.60 (0.54 to 0.68)4.90E-16
6DRB1:74:A0.600.55DRB1:74:A1.58 (1.39 to 1.78)2.04E-12
  • P value less than 5.0×10−8 was considered as cut-off.

  • Case: frequencies of the Non-reference amino-acid in cases.

  • Control: frequencies of the Non-reference amino-acid in controls.