Stepwise conditional analysis on HLA-DQα1:160D in combined cohort, using gender as covariate
CHR | Marker | Case | Control | Non-reference amino-acid | OR (95% CI) | P value |
6 | DRB1:96:H | 0.53 | 0.64 | DRB1:96:H | 0.60 (0.54 to 0.68) | 4.90E-16 |
6 | DRB1:74:A | 0.60 | 0.55 | DRB1:74:A | 1.58 (1.39 to 1.78) | 2.04E-12 |
P value less than 5.0×10−8 was considered as cut-off.
Case: frequencies of the Non-reference amino-acid in cases.
Control: frequencies of the Non-reference amino-acid in controls.