Multivariate analysis models which predict renal survival
| Parameters | Model 1 | Model 2 | Model 3 | ||||||
| HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
| Age at diagnosis | 1.01 | 0.98 to 1.03 | 0.39 | 0.98 | 0.96 to 1.01 | 0.41 | 1.01 | 0.99 to 1.04 | 0.18 |
| AAV subgroups | 0.36 | 0.21 | 0.06 | ||||||
| GPA versus MPA | 2.10 | 0.87 to 5.08 | 0.09 | 2.72 | 1.07 to 6.92 | 0.03 | 4.07 | 1.45 to 11.39 | 0.007 |
| EGPA versus MPA | 0 | 0 n/A | 0.98 | 0.02 | 0 n/A | 0.99 | 0 | 0 n/A | 0.98 |
| RLV versus MPA | 2.22 | 0.86 to 5.75 | 0.09 | 2.20 | 0.80 to 6.05 | 0.12 | 2.92 | 0.99 to 8.60 | 0.05 |
| Histopathological classification | – | – | 0.04 | – | – | 0.08 | – | – | – |
| Focal versus sclerotic | 0.20 | 0.05 to 0.75 | 0.01 | 0.31 | 0.07 to 1.27 | 0.10 | – | – | – |
| Mixed versus sclerotic | 0.32 | 0.11 to 0.87 | 0.02 | 0.25 | 0.08 to 0.76 | 0.01 | – | – | – |
| Crescentic versus sclerotic | 0.57 | 0.23 to 1.41 | 0.22 | 0.53 | 0.21 to 1.29 | 0.16 | – | – | – |
| GFR at diagnosis | – | – | – | 0.90 | 0.86 to 0.95 | <0.001 | – | – | – |
| ANCA renal risk score | – | – | – | – | – | – | – | – | 0.04 |
| Moderate versus low | – | – | – | – | – | – | 5.62 | 0.74 to 42.35 | 0.09 |
| High versus low | – | – | – | – | – | – | 10.48 | 1.32 to 82.88 | 0.02 |
Bold indicates statistically significant values at group level.
AAV, antineutrophil cytoplasmic antibody-associated vasculitis; ANCA, antineutrophil cytoplasmic antibody; EGPA, eosinophilic granulomatosis with polyangiitis; GFR, glomerular filtration rate; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis; N/A, not applicable; RLV, renal-limited vasculitis.