Table 1

Inconsistencies in the frequencies of the top associated amino acids from Guo et al1

Amino acidsGuo et alOR‡Other studies*
Frequency†Hong Kong ChineseKoreans§Japanese
ControlsPatients with RAn=1064n=1209n=3078
DQα1:160D0.200.362.360.210.220.31
DQα1:160A0.220.372.270.780.760.66
DQα1:160S0.020.010.010.020.03
DRβ1:37N0.230.230.49
  • *Taken from the Allele Frequencies Net Database (http://allelefrequencies.net).

  • †Frequencies taken from Guo et al. Figure 3 and supplementary tables 3, 5 and 8 for DQα1 amino acids and from supplementary tables 4, 6 and 8 for DRβ1:37N.

  • ‡OR reported in pages 775 and 776 of Guo et al for DQα1 and DRβ1:37N, respectively.

  • §Results for Koreans were combined from four studies.

  • RA, rheumatoid arthritis.