Schedule of administration of pneumococcal vaccine in AIIRD patients under immunosuppressive therapy based on the CDC recommendations
| History of prior vaccination | Schedule for administration of PCV13 and PPSV23 |
| None or unknown | Administer PCV13 followed in 8 weeks by PPSV23 #1. Administer PPSV23 #2 at least 5 years after PPSV23 #1. |
| One dose PPSV23; zero or unknown PCV13 | Administer PCV13 at least 1 year after PPSV23 #1. Administer PPSV23 #2 at least 5 years after PPSV23 #1 and at least 8 weeks after PCV13. |
| Zero or unknown PPSV23; one dose PCV13 | Administer PPSV23 #1 at least 8 weeks after PCV13. Administer PPSV23 #2 at least 5 years after PPSV23 #1. |
| One dose PPSV23; one dose PCV13 | Administer PPSV23 #2 at least 5 years after PPSV23 #1 and at least 8 weeks after PCV13. |
| Two doses PPSV23; 0 or unknown PCV13 | Administer PCV13 at least 1 year after PPSV23 #2. |
Reference:http://www.immunize.org/catg.d/p3075.pdf
AIIRD, autoimmune inflammatory rheumatic diseases; CDC, Centers for Disease Control and Prevention; PCV13, 13-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine.