Summary statistics for the genome-wide significant association of single nucleotide polymorphisms with adult-onset Still's disease
| SNP | Nearby gene(s) | Chr | Position (hg19) | Risk/non-risk allele | Stage* | RAF in cases | RAF in controls | OR | SE | P values | P_het |
| rs9268791 | HLA-DRA|HLA-DRB5 | 6 | 32 421 073 | T/C | Meta | – | – | 2.363 | 0.096 | 4.10E−19 | 0.686 |
| Discovery | 0.468 | 0.273 | 2.389 | 0.100 | 2.85E−18 | ||||||
| Replication | 0.382 | 0.224 | 2.054 | 0.360 | 4.54E−02 | ||||||
| rs3094178 | HLA-G | 6 | 29 818 000 | C/G | Meta | – | – | 2.139 | 0.135 | 1.97E−08 | 0.806 |
| Discovery | 0.875 | 0.769 | 2.116 | 0.143 | 1.48E−07 | ||||||
| Replication | 0.767 | 0.568 | 2.366 | 0.432 | 4.62E−02 |
*The discovery data set comprises 247 cases and 2163 controls from northern and central China. The replication data set comprises 17 cases and 257 controls from southern China.
Chr, chromosome;P_het, p value for heterogeneity test across different cohorts using Cochran's Q test; RAF, frequency of risk allele;SNP, single nucleotide polymorphism.