Table 2

Adverse events in each arm

Standard treatment armProgrammed treatment armProgrammed treatment arm
TNF-lowTNF-intTNF-high
Observed person weeks8175.383542646.63266.62440.9
Infectious events20
(0.24 per 100 weeks)
22
(0.26 per 100 weeks)
7
(0.26 per 100 weeks)
11
(0.34 per 100 weeks)
4
(0.16 per 100 weeks)
Other events67
(0.82 per 100 weeks)
80
(0.96 per 100 weeks)
31
(1.17 per 100 weeks)
25
(0.77 per 100 weeks)
24
(0.98 per 100 weeks)
Severe infectious events5
(0.06 per 100 weeks)
2
(0.02 per 100 weeks)
1
(0.04 per 100 weeks)
0
(0.00 per 100 weeks)
1
(0.04 per 100 weeks)
Severe other events1
(0.01 per 100 weeks)
5
(0.06 per 100 weeks)
2
(0.08 per 100 weeks)
2
(0.06 per 100 weeks)
1
(0.04 per 100 weeks)
Possible related infectious events15
(0.18 per 100 weeks)
13
(0.16 per 100 weeks)
4
(0.15 per 100 weeks)
5
(0.15 per 100 weeks)
4
(0.16 per 100 weeks)
Possible related other events11
(0.13 per 100 weeks)
17
(0.20 per 100 weeks)
10
(0.38 per 100 weeks)
6
(0.18 per 100 weeks)
1
(0.04 per 100 weeks)
  • TNF, tumour necrosis factor.