Table 1

Association analysis of OAT10/SLC22A13 variant, rs117371763 [Arg377Cys (R377C)], with gout susceptibility

Gout casesControlsp valueOR (95% CI)
C/CC/TT/TMAF (%)C/CC/TT/TMAF (%)
Discovery phase4473123.654274666.050.0140.59 (0.38 to 0.90)
Replication phase8596323.63190020355.020.0150.71 (0.53 to 0.94)
Meta-analysis7.8×10-4 0.67 (0.53 to 0.85)
  • In the meta-analysis, no apparent heterogeneity was observed (p value for Cochran's Q test=0.48, I2=0%).

  • MAF, minor allele frequency.