Table 5

G-CAN endorsed labels and definitions for the disease states of gout

Consensus labelConsensus definition
Pre-clinical states1. Asymptomatic hyperuricaemia*Hyperuricaemia* in the absence of gout.
2. Asymptomatic MSU crystal depositionEvidence of MSU crystal deposition in the absence of gout. MSU crystal deposition may be demonstrated by imaging or microscopic analysis
3. Asymptomatic hyperuricaemia* with MSU crystal depositionHyperuricaemia* with evidence of MSU crystal deposition in the absence of gout. MSU crystal deposition may be demonstrated by imaging or microscopic analysis
Clinical states4. GoutA disease caused by MSU crystal deposition with any of the following clinical presentations (current or prior): gout flare, chronic gouty arthritis, or subcutaneous tophus
5. Tophaceous goutGout with at least one subcutaneous tophus
6. Erosive goutGout with at least one gouty bone erosion
Disease course states7. First gout flareThe first episode of gout flare
8. Recurrent gout flaresMore than one gout flare
Additional recommendation on disease states not addressed by the nomenclatureWhere there is more than one disease state present, these can be combined (eg, tophaceous and erosive gout). Where there are additional elements present, not recognised as disease states, these will be labelled as the recognised disease state with or without additional disease elements (eg, tophaceous gout with chronic gouty arthritis)
  • *In British English, hyperuricaemia.

  • MSU, monosodium urate.