Table 3

Associations detected for each outcome measure by Cox frailty analysis

COVARIATES Cardiac Blocks and/or Q waves and/or Pacemaker Implantation n.events=49* HR; 95% CI; p value Ventricular Arrhytmias
n.events=12 HR; 95% CI; p value
LVEF≤55% and/or CHF n.events=19 HR; 95% CI; p value
EScSG activity index≥ 3 2.12; 0.98–4.57; 0.06 3.79; 1.04–13.82; 0.04
Low dose ASA 0.53; 0.26–1.08; 0.08
Vasodilators 0.32; 0.10–1.02; 0.05
  • *Two patients developed 2 events (1 cardiac block and pacemaker implantation; 1 cardiac block and Q wave).

  • ASA, acetylsalicylic acid; CHF, congestive heart failure; EScSG, European Scleroderma Study Group; LVEF, left ventricular ejection fraction.