Table 1

Clinical characteristics of the patients performed serum analysis

Disease groupHCSSSScPBCOverlap
n=68n=112n=35n=10n=44
Female %, (n)82 (56)95 (106)86 (30)100 (10)100 (44)
Age median (IQR)44 (31–50)59 (47–72)59 (50–71)60 (57–72)64 (54–74)
ACA positive % (n)NA13 (14)34 (12)30 (3)70 (31)
Anti-CENP-B antibody positive % (n)1.5 (1)13 (14)37 (13)30 (3)73 (32)
Disease type/complicated disease, npSS 71
sSS 15
non-SS 26
dcSSc 10
lcSSc 25
SS 32
SSc 37
PBC 30
  • dcSSc, diffuse cutaneous SSc; lcSSc, limited cutaneous SSc; NA, not accessed; PBC, primary biliary cirrhosis; pSS, primary Sjögren's syndrome; SS, Sjögren's syndrome; sSS, secondary Sjögren's syndrome.