Table 2

Values of laboratory tests in patients with MAS and with active sJIA without MAS*

Laboratory testMAS
(n=362)
sJIA without MAS
(n=404)
P value
White cell count, x 109/L9.9 (4.6–16.3)16.8 (12.1–21.9)<0.0001
Neutrophil count, 109/L5.4 (2.3–11.5)11.9 (7.7–17.8)<0.0001
Haemoglobin, g/L9.8 (8.3–11.1)10.1 (9.1–11.2)0.019
Platelet count, x 109/L144 (86–269)498 (377–615)<0.0001
Aspartate aminotransferase, units/L134 (58–338)28 (20–39)<0.0001
Alanine aminotransferase, units/L96 (37–234)18 (11–34)<0.0001
Lactate dehydrogenase, units/L1203 (666–2345)438 (291–611)<0.0001
Triglycerides, mg/dL234 (151–318)124 (91–142)<0.0001
Albumin, g/dL3.1 (2.6–3.5)3.5 (3–4)<0.0001
Serum sodium, mmol/L136 (132–138)138 (135–140)<0.0001
Fibrinogen, mg/dL267 (152–437)559 (463–720)<0.0001
D-dimer, ng/mL2996 (1094–7550)2050 (501–4064)0.004
Ferritin, ng/mL5353 (1500–13 040)502 (158–1627)<0.0001
Erythrocyte sedimentation rate, mm/hour48 (19–84)78 (56–100)<0.0001
C-reactive protein, mg/dL9.2 (3.5–17.7)8.9 (4.8–15.3)0.99
  • Davì et al, Arthritis Rheumatol 2014;66:2871–80.

  • *Data are medians (interquartile ranges).

  • MAS, macrophage activation syndrome; sJIA, systemic juvenile idiopathic arthritis.