Table 3

Posterior probability of each demographic, clinical and laboratory variable to enter the logistic regression models with the best performance in the discrimination of patients with MAS from patients with sJIA without MAS (N=613)

Posterior probability
Demographic characteristics
 Gender0.25
 Age at onset0.15
Clinical features
 Central nervous system involvement1.0
 Active arthritis0.96
 Haemorrhagic manifestations0.81
 Evanescent rash0.76
 Generalised lymphadenopathy0.43
 Hepatomegaly0.33
 Fever0.14
 Splenomegaly0.13
Laboratory tests
 Platelet count0.99
 Fibrinogen0.99
 Lactate dehydrogenase0.99
 Ferritin0.86
 C-reactive protein0.75
 Alanine aminotransferase0.64
 Triglycerides0.55
 Neutrophil count0.31
 White cells count0.25
 Albumin0.18
 Aspartate aminotransferase0.17
 Erythrocyte sedimentation rate0.14
 Haemoglobin0.12
  • Variables with a posterior probability >0.80 were selected for inclusion in the final model.

  • MAS, macrophage activation syndrome; sJIA, systemic juvenile idiopathic arthritis.