Table 1

Study participant demographics*

VariableTransitioned relatives n=56Non-transitioned relatives n=380Unaffected controls n=122P value
Age at baseline: mean (median)±SD47.4 (48.5)±12.147.2 (48.0)±15.8†51.1 (51.0)±12.7 0.01
Time between recontact (years): mean (median)±SD5.9 (5.1)±3.56.3 (5.4)±3.9†NA0.50
Sex: female (n,%)‡49 (87.5)316 (83.2)106 (86.9)0.49
Race (n,%)
 European American
 African American
 Native American
 Asian/Pacific Islander
 Hispanic
43 (76.8)
9 (16.1)
4 (7.1)
0 (0.0)
0 (0.0)
279 (73.4)
55 (14.5)
18 (4.7)
17 (4.5)
11 (2.9)
89 (73.0)
15 (12.3)
9 (7.4)
5 (4.1)
4 (3.2)
0.004
ANA positive baseline (n,%)§43 (76.8)183 (48.2)15 (12.3) < 0.0001
Number of baseline ACR Criteria
 0–1
 2
 3
7 (12.5)
23 (41.1)
26 (46.4)
291 (76.5)
74 (19.5)
15 (4.0)
ND < 0.0001
  • *P value for trend. Statistically significant values (p<0.05) are in bold.

  • †Not significant between transitioned and non-transitioned relatives by Mann-Whitney U test.

  • ‡Not significant between transitioned and non-transitioned relatives by Fisher’s exact test.

  • §P<0.0001 between transitioned and non-transitioned relatives by Fisher’s exact test.

  • ACR, American College of Rheumatology; ANA, antinuclear antibodies; NA, not applicable; ND, not determined.