Table 1

Baseline demographic and clinical details for the MEMO cohort

Baseline characteristicMedian (IQR)
Age (years)65.5 (54–70)
Female gender (%)65
Weight (kg)76.9 (67.3–85.4)
Serum creatinine (µM)71.5 (67.0–79.0)
eGFR (mL/min/1.73 m2)* 84 (76–99)
Serum albumin (g/L)37 (37–39)
MTX dose (mg/week)15 (7.5–25)
Taking concomitant folic acid (%)100
Taking concomitant NSAIDs (%)20
  • *Calculated using the MDRD eGFR calculation.

  • †Median (range).

  • MDRD, Modification of Diet in Renal Disease; MEMO, Measurement of MTX and 7-OH-MTX metabolites in urine of patients with rheumatoid arthritis; MTX, methotrexate; NSAID, non-steroidal anti-inflammatory drug; 7-OH-MTX, 7-hydroxy-MTX; eGFR, estimated glomerular filtration rate.