Baseline demographic and clinical details for the MEMO cohort
| Baseline characteristic | Median (IQR) |
| Age (years) | 65.5 (54–70) |
| Female gender (%) | 65 |
| Weight (kg) | 76.9 (67.3–85.4) |
| Serum creatinine (µM) | 71.5 (67.0–79.0) |
| eGFR (mL/min/1.73 m2)* | 84 (76–99) |
| Serum albumin (g/L) | 37 (37–39) |
| MTX dose (mg/week) | 15 (7.5–25)† |
| Taking concomitant folic acid (%) | 100 |
| Taking concomitant NSAIDs (%) | 20 |
*Calculated using the MDRD eGFR calculation.
†Median (range).
MDRD, Modification of Diet in Renal Disease; MEMO, Measurement of MTX and 7-OH-MTX metabolites in urine of patients with rheumatoid arthritis; MTX, methotrexate; NSAID, non-steroidal anti-inflammatory drug; 7-OH-MTX, 7-hydroxy-MTX; eGFR, estimated glomerular filtration rate.