Domain | Item | Original | Modification | Revised | Simplified |
Constitutional | Fever | 13 | 13 | 2 | |
Haematological | Leucopenia | 12 | +7 | 19 | 3 |
Thrombocytopenia | 26 | 26 | 4 | ||
Autoimmune haemolysis | 28 | 28 | 4 | ||
Neuropsychiatric | Delirium | 12 | 12 | 2 | |
Psychosis | 20 | 20 | 3 | ||
Seizure | 34 | 34 | 5 | ||
Mucocutaneous | Alopecia | 13 | 13 | 2 | |
Oral ulcers | 14 | 14 | 2 | ||
Subacute lupus erythematosus (SCLE)/discoid lupus erythematosus (DLE) | 29 | 29 | 4 | ||
Acute cutanoues lupus erythematsous (ACLE) | 38 | 38 | 6 | ||
Serosal | Effusion | 34 | 34 | 5 | |
Acute pericarditis | 38 | 38 | 6 | ||
Musculoskeletal | Joint involvement | 34 | +4 | 38 | 6 |
Renal | Proteinuria | 27 | 27 | 4 | |
Class II/V | 55 | 55 | 8 | ||
Class III/IV | 74 | 74 | 10 | ||
APL antibodies | Antiphospholipid | 13 | 13 | 2 | |
Complements | C3 or C4 low | 19 | 19 | 3 | |
C3 and C4 low | 27 | 27 | 4 | ||
SLE-specific antibodies | Anti-Sm | 40 | 40 | 6 | |
Anti-dsDNA | 38 | 38 | 6 |
Weights derived from the phase III consensus meeting with multicriteria decisions analysis (original), added points for leucopenia and joint involvement (modification), the resulting weights (revised) and the final simplified weights (simplified).
SLE, systemic lupus erythematosus; anti-Sm, anti-Smith; dsDNA, double-stranded DNA; dsDNA, double-stranded DNA;