Operating characteristics of the new classification criteria compared with the ACR 1997 and SLICC 2012 classification criteria in the derivation and the validation cohorts
ACR 1997 criteria | SLICC 2012 criteria | EULAR/ACR 2019 criteria | |
Derivation | |||
Sensitivity (95% CI) | 0.85 [0.81 to 0.88] | 0.97 [0.95 to 0.98] | 0.98 [0.97 to 0.99] |
Specificity (95% CI) | 0.95 [0.93 to 0.97] | 0.90 [0.87 to 0.92] | 0.96 [0.95 to 0.98] |
Combined (95% CI) | 1.80 [1.76 to 1.83] | 1.87 [1.84 to 1.90] | 1.94 [1.92 to 1.96] |
Validation | |||
Sensitivity (95% CI) | 0.83 [0.80 to 0.85] | 0.97 [0.95 to 0.98] | 0.96 [0.95 to 0.98] |
Specificity (95% CI) | 0.93 [0.91 to 0.95] | 0.84 [0.80 to 0.87] | 0.93 [0.91 to 0.95] |
Combined (95% CI) | 1.76 [1.73 to 1.80] | 1.80 [1.77 to 1.84] | 1.90 [1.87 to 1.92] |
ACR, American College of Rheumatology; EULAR, European League Against Rheumatism; SLICC, Systemic Lupus International Collaborating Clinics.