Table 3

Number of drug target genes identified for CHi-C genes enriched in significant pathways (Benjamini-Hochberg) for each disease, corresponding to the number of drugs and the potential for non-existing pathway gene targets for drug repositioning

DiseaseGenes identified by CHi-C (n)Genes which are existing drug targets (n)Drugs identified (n)Drugs currently used (n)Drugs for potential repositioning (n)Potential pathway targets (n)Potential pathway drugs (n)
RA501338830283398
PsA922024787
JIA102404205325
All591439831307412
  • CHi-C, Capture Hi-C; JIA, juvenile idiopathic arthritis; PsA, psoriatic arthritis; RA, rheumatoid arthritis.