Differences between the SLE and HC groups for each of the CANTAB outcome measures
| Variable* | Measurement | SLE, n=36 | HC, n=30 | P value |
| Mean (SD), Median (LQ, UQ), n (%) | ||||
| PAL+ (visual memory and new learning) | Total errors (adjusted) | 29.50 (19.00, 79.75) | 24 (10.75, 48.75) | P=0.095 |
| VRM (verbal memory) | Free recall – total correct (Max.=18) | 10 (8, 13) | 10 (8.75, 14) | P=0.327 |
| RVP (attention) | Total hits (Max.=27) | 13 (12, 20) | 20 (15.75, 22) | P= 0.002 |
| ERT (emotional processing) | Average percentage correct – total (%) | 61.49 (8.85) | 66.94 (9.36) | P= 0.019 |
| Overall mean response latency – total (ms)+ | 1626.10 (1411.71, 2274.22) | 1343.15 (1152.27, 1744.23) | P= 0.012 | |
| OTS+ (executive function) | Mean choices to correct | 1.40 (1.27, 1.73) | 1.33 (1.18, 1.62) | P=0.484 |
| SWM+ (working memory) | Between errors | 108.41 (57.96) | 94.73 (52.36) | P=0.328 |
Missing data: VRM: 1 SLE, ERT: 1 SLE; RVP: 1 SLE; SWM: 2 SLE; OTS: 1 SLE.
P-values in bold are significant at <0.05.
*Higher scores indicate better performance except where indicated with a “+”.
ERT, emotional recognition task; OTS, one touch stockings; Pal, paired associate learning; RVP, rapid information visual processing; SWM, spatial working memory; VRM, verbal recognition memory.