T able 4

Summary of serum levels of COMP, resistin, MCP-1, HGF and NGF in validation cohort of patients with PsA (n=73) and OA (n=75)

BiomarkersPsA (n=73)*OA (n=75)*P value†
COMP, ng/mL217.3 (182.9–278.3)210.3 (166.6–264.7)0.3435
Resistin, ng/mL36.0 (28.3–51.9)24.6 (19.8–34.7)<0.0001
HGF, ng/mL0.6 (0.5–1.0)0.2 (0.2–0.3)<0.0001
MCP-1, pg/mL370.0 (269.8–458.4)127.6 (106.3–162.7)<0.0001
NGF, pg/mL3.0 (2.0–4.3)4.5 (3.3–6.8)<0.0001
  • *Median (IQR).

  • †Wilcoxon rank-sum test.

  • COMP, cartilage oligomeric matrix protein; HGF, hepatocyte growth factor; MCP-1, monocyte chemoattractant protein-1; NGF, nerve growth factor; OA, osteoarthritis.