Table 2

Primary outcome of fatigue impact at 26 weeks

ControlRAFTAdjusted* mean difference
(95% CI)
P value
n (%)†Week 0
Mean (SD)
Week 26
Mean (SD)
n (%)†Week 0
Mean (SD)
Week 26
Mean (SD)
BRAF-NRS effect152 (96.2)7.23 (1.6)6.36 (2.42)156 (89.1)7.10 (1.7)5.74 (2.41)−0.59 (−1.11 to -0.06)0.03
  • *Linear regression adjusted for baseline BRAF-NRS impact and centre.

  • †Percentage of total randomised (Control 158, RAFT 175).

  • BRAF-NRS, Bristol RA Fatigue Numerical Rating Scale.