Table 3

Reason for withdrawal in switchers and non-switchers

Switchers
N=1621
Non-switchers
N=440
Reason, n (% of withdrawals)
 Lack of effect137 (46)48 (34)
 Adverse events77 (26)*14 (10)
 Several reasons9 (3)1 (1)
 Cancer6 (2)11 (8)
 Remission8 (3)10 (7)
 Pregnancy4 (1)3 (2)
 Death9 (3)15 (10)
 Infection3 (1)8 (6)
 Loss to follow-up1 (2)9 (6)
 Surgery2 (1)1 (1)
 Other14 (5)18 (13)
 Not stated29 (10)7 (5)
Withdrawals, total, n (%)299 (100)145 (100)
  • *Adverse events during biosimilar etanercept (SB4) treatment in switchers (77 patients): anxiety 1 patient, arthralgia 1, bladder dysfunction 1, blurred vision 1, chest pain 2, diarrhoea 4, dizziness 2, dyspnoea 2, erectile dysfunction 1, fatigue 1, fever 2, hair loss 1, headache/migraine 9, hyperhidrosis 2, hypertension 1, hypotension 1, infections 2, leg cramps 2, leucopenia 3, local injection problems 3, myalgia 2, nausea 4, neuropathies 1, psoriasis worsening or pustulosis 2, rash/itching 11, not stated 39 (total=101 events).