Serious adverse events during study follow-up
| Rituximab group (n=13) | Placebo (n=3) |
| Atypical thoracic pain (normal ECG) | Arterial occlusion right foot |
| Elective total hip replacement for OA | Elective total hip replacement for OA |
| Elective sigmoid resection after pre-existent recurring diverticulitis | Headache and concentration problems (neurological tests including MRI brain normal) |
| Elective surgery for nephrolithiasis | |
| Vertebral fracture after trauma | |
| Elective herniated disc surgery | |
| Elective knee arthroplasty for OA | |
| Hospitalisation for COPD exacerbation (n=2) | |
| Hospitalisation for depression | |
| Thrombosis upper extremity; pulmonary embolism | |
| STEMI caused by left main coronary artery stenosis | |
| Pre-existent bladder atony |
COPD, chronic obstructive pulmonary disease; OA, osteoarthritis; STEMI, ST elevation myocardial infarction.