Table 2

Summary of primary outcomes in adult-onset IgA vasculitis (IgAV) cases and corresponding controls

HypertensionIschaemic heart diseaseStroke/TIAVenous thromboembolismChronic kidney diseaseAll-cause mortality
IgAVControlIgAVControlIgAVControlIgAVControlIgAVControlIgAVControl
Patients, n230549212689543527605548277655942487522528285655
Numbers of outcomes19631553104681072846134185238348
Person-years 12 847.6028 174.4615 97432 542.3816 552.3933 468.5816 771.0733 813.9515 359.9232 167.3117 085.1334 391.52
Incidence rate (per 1000 person-years)15.2611.183.323.203.143.261.671.368.725.7513.9310.12
Crude HR (95% CI)1.36 (1.14–1.63)1.04 (0.75–1.44)0.96 (0.69–1.34)1.22 (0.76–1.96)1.52 (1.22–1.90)1.37 (1.17–1.62)
P values0.0010.8290.8140.401<0.001<0.001
Adjusted HR (95% CI)1.42 (1.19–1.70)1.08 (0.77–1.52)0.95 (0.68–1.32)1.21 (0.76–1.95)1.54 (1.23–1.93)1.27 (1.07–1.50)
P values<0.0010.6370.7580.424<0.0010.006