Table 2

Associations in white HLA-B*27-negative patients with AS

AlleleCase frequency %Control frequency %No. casesNo. controlsORP values
A*0114.514.211010301.031.00
A*0224.527.711010300.850.56
A*0310.016.611010300.560.10
A*117.33.511010302.170.09
A*2412.78.811010301.500.24
A*29 9.1 3.5 110 1030 2.76 0.01
B*07:00 10.2 15.4 472 1828 0.62 0.005
B*08:009.321.947218280.780.17
B*13:002.52.747218280.950.99
B*14:004.43.147218281.450.20
B*38:00 3.2 2.8 472 1828 2.04 0.04
B*40 all7.415.347218280.900.70
B*40:015.38.147218280.870.60
B*49:00 2.5 1.1 472 1828 2.36 0.03
B*51:004.73.847218281.230.49
B*52:00 2.8 1.0 472 1828 2.85 0.006
B*57:00 1.7 3.7 472 1828 0.45 0.04
C*01:002.71.311011462.110.43
C*02:000.92.211011460.410.59
C*03:0011.814.611011460.790.52
C*04:0012.711.911011461.080.91
C*05:005.59.611011460.540.21
C*06:007.310.511011460.670.37
C*07:0030.032.911011460.870.61
DRB1*01:014.77.91489480.580.24
DRB1*01:031.41.81489480.750.97
DRB1*03:016.812.21489480.520.07
DRB1*04:044.72.31489482.090.16
DRB1*11:00 17.6 9.6 148 948 2.01 0.005
DRB1*15:01 6.1 14.8 148 948 0.37 0.006
DQB1*02:01 6.8 12.7 148 948 0.50 0.05
DQB1*03:0126.419.21489481.510.06
DQB1*03:028.88.51489481.591.00
DQB1*05:0110.211.41489480.740.40
DQB1*06:02 6.8 15.1 148 948 0.41 0.009
DPB1*01:012.94.91026780.590.54
DPB1*02:0112.810.31026781.470.25
DPB1*03:0111.18.11026781.420.03
DPB1*04:0142.544.31026780.930.46
DPB1*04:0212.714.11026780.880.38
  • Significant associations are highlighted in bold numbers.

  • *The ‘-co’ (combined) nomenclature for B*27 and B40 indicates the grouping of all such 4-digit alleles into 2-digit only.

  • AS, ankylosing spondylitis.