Table 1

Baseline characteristics of patients with rheumatoid arthritis with versus without baseline depression/anxiety according to the MCS ≤38 or MH ≤56

All patients (n=293)Depressed/anxious (n=81)Not depressed/anxious (n=212)P value
Age, mean (SD)57 (15)54 (15)58 (14)0.02
Female, n (%)193 (66)58 (72)135 (64)0.20
Symptom duration in months, median (IQR)3 (1–8)3 (1–7)3 (1–8)0.72
Currently smoking, n (%)65 (23)25 (33)40 (20)0.08
ACPA-positive, n (%)162 (55)43 (53)119 (56)0.64
ESR (mm/hour), median (IQR)28 (14–41)28 (14–42)28 (14–41)0.85
CRP (mg/L), median (IQR)10 (3–22)7 (3–26)10 (3–20)0.76
EGA, mean (SD)49 (20)49 (24)49 (19)0.44
PGA, mean (SD)45 (27)54 (27)42 (26)0.001
Pain, mean (SD)60 (25)63 (24)58 (25)0.92
68-TJC, median (IQR)10 (5–17)11 (6–19)10 (5–16)0.18
66-SJC, median (IQR)5 (2–11)5 (2–10)6 (2–11)0.14
DAS44, mean (SD)2.9 (0.8)3.0 (0.8)2.9 (0.8)0.45
  • Pain measured by a 0–100 VAS.

  • 68-TJC, 68 tender joint counts; 66-SJC, 66 swollen joint counts; ACPA, anticitrullinated peptide antibody; CRP, C reactive protein; DAS44, 44-joint Disease Activity Score; EGA, evaluator’s global assessment by a 0–100 VAS; ESR, erythrocyte sedimentation rate; MCS, mental component summary; MH, mental health subscale; PGA, patient’s global assessment by a 0–100 VAS; VAS, Visual Analogue Scale.