Baseline characteristics of patients with rheumatoid arthritis with versus without baseline depression/anxiety according to the MCS ≤38 or MH ≤56
| All patients (n=293) | Depressed/anxious (n=81) | Not depressed/anxious (n=212) | P value | |
| Age, mean (SD) | 57 (15) | 54 (15) | 58 (14) | 0.02 |
| Female, n (%) | 193 (66) | 58 (72) | 135 (64) | 0.20 |
| Symptom duration in months, median (IQR) | 3 (1–8) | 3 (1–7) | 3 (1–8) | 0.72 |
| Currently smoking, n (%) | 65 (23) | 25 (33) | 40 (20) | 0.08 |
| ACPA-positive, n (%) | 162 (55) | 43 (53) | 119 (56) | 0.64 |
| ESR (mm/hour), median (IQR) | 28 (14–41) | 28 (14–42) | 28 (14–41) | 0.85 |
| CRP (mg/L), median (IQR) | 10 (3–22) | 7 (3–26) | 10 (3–20) | 0.76 |
| EGA, mean (SD) | 49 (20) | 49 (24) | 49 (19) | 0.44 |
| PGA, mean (SD) | 45 (27) | 54 (27) | 42 (26) | 0.001 |
| Pain, mean (SD) | 60 (25) | 63 (24) | 58 (25) | 0.92 |
| 68-TJC, median (IQR) | 10 (5–17) | 11 (6–19) | 10 (5–16) | 0.18 |
| 66-SJC, median (IQR) | 5 (2–11) | 5 (2–10) | 6 (2–11) | 0.14 |
| DAS44, mean (SD) | 2.9 (0.8) | 3.0 (0.8) | 2.9 (0.8) | 0.45 |
Pain measured by a 0–100 VAS.
68-TJC, 68 tender joint counts; 66-SJC, 66 swollen joint counts; ACPA, anticitrullinated peptide antibody; CRP, C reactive protein; DAS44, 44-joint Disease Activity Score; EGA, evaluator’s global assessment by a 0–100 VAS; ESR, erythrocyte sedimentation rate; MCS, mental component summary; MH, mental health subscale; PGA, patient’s global assessment by a 0–100 VAS; VAS, Visual Analogue Scale.