Table 1

Selected HLA Class I and II associations with AS in whites overall

Allele	Cases frequency %	Control freqquency %	# Cases	# Controls	OR	P values
A*01	8.6	13.9	1326	1134	0.58	3.44×10^–5
A*02	35.1	27.9	1326	1134	1.40	1.56×10^–4
A*03	8.2	16.3	1326	1134	0.50	<1×10^–8
B*07:00	5.9	15.0	3896	1980	0.36	<1×10^–8
B*08:00	11.5	20.9	3896	1980	0.49	<1×10^–8
B*13:00	1.5	2.5	3896	1980	0.60	0.01
B*14:00	2.9	2.9	3896	1980	1.00	1.00
B*15:00	3.3	7.1	3896	1980	0.45	<1×10^–8
B*27:00	46.1	3.8	3896	1980	21.4	<1×10^–8
B*35:00	4.2	8.7	3896	1980	0.46	<1×10^–8
B*38:00	1.3	1.5	3896	1980	0.91	0.78
B*40 all	5.4	7.6	3896	1980	0.69	0.001
B*40:01	4.4	5.7	3896	1980	0.76	0.03
B*40:02	0.7	1.2	3896	1980	0.59	0.09
B*44:00	8.2	15.0	3896	1980	0.51	<1×10^–8
B*51:00	2.7	3.8	3896	1980	0.70	0.03
B*52:00	0.9	0.9	3896	1980	1.02	0.95
B*57:00	1.3	3.7	3896	1980	0.34	<1×10^–8
C*01:00	19.2	3.0	1302	1290	7.62	<1×10^–8
C*06:00	4.5	9.8	1302	1290	0.43	2.1×10^–7
C*07:00	15.9	31.2	1302	1290	0.42	<1×10^–8
DRB1*01:01	16.5	9.0	1580	1416	2.00	<1×10^–8
DRB1*01:03	4.6	2.0	1580	1416	2.34	0.0001
DRB1*03:01	6.0	12.0	1580	1416	0.46	<1×10^–8
DRB1*04:04	6.5	2.5	1580	1416	2.72	3.0×10^–7
DRB1*15:01	8.7	14.7	1580	1416	0.56	4.8×10^–7
DQB1*02:01	6.3	12.7	1580	1416	0.46	<1×10^–9
DQB1*03:01	26.4	19.2	1580	1416	1.29	0.006
DQB1*03:02	14.3	9.2	1580	1416	1.65	2.0×10^–5
DQB1*05:01	19.9	12.6	1580	1416	1.71	1.2×10^–7
DQB1*06:02	9.2	15.1	1580	1416	0.57	<1×10^–9
DPB1*02:01	12.8	10.3	1264	768	1.28	0.10
DPB1*03:01	11.1	8.1	1264	768	1.42	0.03
DPB1*04:01	42.5	44.3	1264	768	0.93	0.46
DPB1*04:02	12.7	14.2	1264	768	0.88	0.38

AS, ankylosing spondylitis.